Background A more accurate means of prognostication in breast cancer will improve the
selection of patients for adjuvant systemic therapy. Methods Using microarray analysis to …

Breast cancer patients with the same stage of disease can have markedly different treatment
responses and overall outcome. The strongest predictors for metastases (for example, …

Ascertaining the impact of uncharacterized perturbations on the cell is a fundamental problem
in biology. Here, we describe how a single assay can be used to monitor hundreds of …

We describe a flexible system for gene expression profiling using arrays of tens of thousands
of oligonucleotides synthesized in situ by an ink-jet printing method employing standard …

Based on the hypothesis that features of the molecular program of normal wound healing
might play an important role in cancer metastasis, we previously identified consistent features …

Genome-wide transcript profiling was used to monitor signal transduction during yeast
pheromone response. Genetic manipulations allowed analysis of changes in gene expression …

Persistent aromatic pollutants are widely found in the effluents from the pharmaceutical,
petrochemical, dyestuff, pesticide, and other industries. Because of their high solubility in water, …

A data anomaly was observed that affected the uniformity and reproducibility of fluorescent
signal across DNA microarrays. Results from experimental sets designed to identify potential …

Motivation: In microarray gene expression studies, the number of replicated microarrays is
usually small because of cost and sample availability, resulting in unreliable variance …

Breast cancer comprises a group of distinct subtypes that despite having similar histologic
appearances, have very different metastatic potentials. Being able to identify the biological …