To meet the high-efficiency question answering needs of existing patients and doctors, this
system integrates medical professional knowledge, knowledge graphs, and question …

Vortioxetine is a novel anti-major depression disorder drug with a high safety profile
compared with other similar drugs. However, little research has been done on drug-drug …

Cytochrome P450 (P450) 2C9 is an important member of the P450 enzyme superfamily,
with 58 CYP2C9 allelic variants previously reported. Genetic polymorphisms of CYP2C9 …

The knowledge graph can make more accurate personalized recommendations for the
recommendation system, but it is also interpretative and has traces to follow. The purpose of the …

Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic enzyme that metabolizes a large
number of therapeutic drugs. To date, more than 100 CYP2D6 allelic variants have been …

CYP2D6 is an important member of the cytochrome P450 (CYP450) enzyme superfamily, we
recently identified 22 CYP2D6 alleles in the Han Chinese population. The aim of this study …

The objective of this study were to investigate the effect of orally administered resveratrol on
the pharmacokinetics of aripiprazole (APZ) in rat, and the inhibitory effects of resveratrol on …

Cytochrome P450 2D6 (CYP2D6) is a highly polymorphic enzyme that catalyzes the
metabolism of a great number of therapeutic drugs. Up to now, >100 allelic variants of CYP2D6 …

Objective: The aim of this article was to assess the catalytic activities of 24 cytochrome P450
2D6 (CYP2D6) variants found in the Chinese population toward atomoxetine in vitro as well …

Cytochrome P450 enzyme 2D6 (CYP2D6) is an important member of the cytochrome P450
enzyme superfamily, with more than 100 CYP2D6 allelic variants being previously reported. …