Effect of camrelizumab vs placebo added to chemotherapy on survival and progression-free survival in patients with advanced or metastatic esophageal squamous …

…, L Chen, Y He, W Ren, S Luo, G Zhao, Y Lin, L Chen… - Jama, 2021 - jamanetwork.com
Importance Standard first-line therapy for advanced or metastatic esophageal carcinoma is
chemotherapy, but the prognosis remains poor. Camrelizumab (an anti–programmed death …

[HTML][HTML] Neoadjuvant chemoradiotherapy followed by surgery versus surgery alone for locally advanced squamous cell carcinoma of the esophagus …

H Yang, H Liu, Y Chen, C Zhu, W Fang… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose The efficacy of neoadjuvant chemoradiotherapy (NCRT) plus surgery for locally
advanced esophageal squamous cell carcinoma (ESCC) remains controversial. In this trial, we …

Hydrothermal synthesis and gas sensing characters of ZnO nanorods

X Jiaqiang, C Yuping, C Daoyong, S Jianian - Sensors and Actuators B …, 2006 - Elsevier
ZnO nanorods are prepared by a hydrothermal process with cetyltrimethylammonium bromide
(CTAB) and zinc powder at 182C. The samples are characterized by X-ray diffraction (XRD…

Long-term efficacy of neoadjuvant chemoradiotherapy plus surgery for the treatment of locally advanced esophageal squamous cell carcinoma: the NEOCRTEC5010 …

H Yang, H Liu, Y Chen, C Zhu, W Fang, Z Yu… - JAMA …, 2021 - jamanetwork.com
Importance The prognosis of patients with locally advanced esophageal squamous cell
carcinoma (ESCC) remains poor after surgery. Neoadjuvant chemoradiotherapy (NCRT) has …

[HTML][HTML] Hepatic gene expression profiles differentiate presymptomatic patients with mild versus severe nonalcoholic fatty liver disease

…, SS Choi, GA Michelotti, DD Hampton, Y Chen… - …, 2014 - Wiley Online Library
Clinicians rely upon the severity of liver fibrosis to segregate patients with well‐compensated
nonalcoholic fatty liver disease (NAFLD) into subpopulations at high‐ versus low‐risk for …

[PDF][PDF] Osteopontin is induced by hedgehog pathway activation and promotes fibrosis progression in nonalcoholic steatohepatitis

…, TA Pereira, M Zdanowicz, P Malladi, Y Chen… - …, 2011 - Wiley Online Library
Nonalcoholic steatohepatitis (NASH) is a leading cause of cirrhosis. Recently, we showed
that NASH‐related cirrhosis is associated with Hedgehog (Hh) pathway activation. The gene …

NKT-associated hedgehog and osteopontin drive fibrogenesis in non-alcoholic fatty liver disease

…, IS Chan, GF Karaca, T de Almeida Pereira, Y Chen… - Gut, 2012 - gut.bmj.com
Objective Immune responses are important in dictating non-alcoholic steatohepatitis (NASH)
outcome. We previously reported that upregulation of hedgehog (Hh) and osteopontin (OPN…

[HTML][HTML] A signature of saliva-derived exosomal small RNAs as predicting biomarker for esophageal carcinoma: a multicenter prospective study

…, K Durante, J Li, F Zhou, Y Guo, S Chen, Y Chen… - Molecular cancer, 2022 - Springer
Background The tRNA-derived small RNAs (tsRNAs) are produced in a nuclease-dependent
manner in responses to variety of stresses that are common in cancers. We focus on a …

Hedgehog controls hepatic stellate cell fate by regulating metabolism

Y Chen, SS Choi, GA Michelotti, IS Chan… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: The pathogenesis of cirrhosis, a disabling outcome of defective
liver repair, involves deregulated accumulation of myofibroblasts derived from quiescent …

Single-crystalline orthorhombic molybdenum oxide nanobelts: synthesis and photocatalytic properties

Y Chen, C Lu, L Xu, Y Ma, W Hou, JJ Zhu - CrystEngComm, 2010 - pubs.rsc.org
Single crystalline MoO3 nanobelts with width of 200–300 nm and the length up to several tens
of micrometres were prepared by a facile hydrothermal method and characterized. Based …