Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode

S Takeda, Y Kitajima, Y Ishii, Y Nishimura… - Drug metabolism and …, 2006 - ASPET
Glucuronidation of morphine in humans is predominantly catalyzed by UDP-glucuronosyltransferase
2B7 (UGT2B7). Since our recent research suggested that cytochrome P450s (…

MET-induced CD73 restrains STING-mediated immunogenicity of EGFR-mutant lung cancer

…, M Saigi, T Tani, BF Springer, H Shibata, S Kitajima… - Cancer research, 2022 - AACR
MET amplification upregulates CD73 to suppress tumor cell STING induction and T-cell
responsiveness in TKI-resistant, EGFR-mutated lung cancer, identifying a strategy to enhance …

[HTML][HTML] COVID-19 risk assessment at the opening ceremony of the Tokyo 2020 Olympic Games

M Murakami, F Miura, M Kitajima, K Fujii… - Microbial risk …, 2021 - Elsevier
The 2020 Olympic/Paralympic Games have been postponed to 2021, due to the COVID-19
pandemic. We developed a model that integrated source–environment–receptor pathways to …

TREX1 Inactivation Unleashes Cancer Cell STING–Interferon Signaling and Promotes Antitumor Immunity

…, PC Gokhale, D Liu, R Uppaluri, S Kitajima… - Cancer Discovery, 2024 - AACR
Kitajima reports grants from Boehringer-Ingelheim outside the submitted work. J. Cain, B. …
We thank Minyue Chen, Yurie Yamamoto, Connor Purcell, Pieter J Schol, Madelyn Cueva, and …

Biosensing by in situ Infrared Spectroscopy

M Niwano, A Hirano-Iwata, M Honda, N Kitajima… - Analytical …, 2015 - jstage.jst.go.jp
We are investigating reactions at Si surfaces and interfaces using infrared spectroscopy in
the multiple internal reflection geometry (MIR-IRAS). This technique, in which infrared light …

The Predicament and the Reflexive Turn

Y Kai - Review of Japanese Culture and Society, 2019 - JSTOR
… Photographs by Tsuchida and Kitajima produced with a large format camera appear …
Kitajima, the change of style is too great of a significance to overlook. In a 2001 interview, Kitajima

[BOOK][B] The Photographer Under Pressure: Nakahira Takuma as a Body in the World, 1968–1977

DP Abbe - 2023 - search.proquest.com
Many art historical discussions take a philosophical approach to photography, in which the
medium becomes an ontological object. This dissertation proceeds instead from the subject …

[HTML][HTML] Trends in the effect of COVID-19 on consultations for persons with clinical and subclinical eating disorders

K Kawai, H Tachimori, Y Yamamoto, Y Nakatani… - BioPsychoSocial …, 2023 - Springer
Background The coronavirus disease 2019 (COVID-19) pandemic has increased the risk of
individuals developing eating disorders and has exacerbated existing eating disorders. This …

[HTML][HTML] Mitochondrial reactive oxygen species are essential for the development of psoriatic inflammation

S Mizuguchi, K Gotoh, Y Nakashima… - Frontiers in …, 2021 - frontiersin.org
Psoriasis is a common immune-mediated, chronic, inflammatory skin disease that affects
approximately 2–3% of the population worldwide. Although there is increasing evidence …

Prevalence of hepatitis E virus (HEV) infection in wild boars (Sus scrofa leucomystax) and pigs in Gunma Prefecture, Japan

C Sakano, Y Morita, M Shiono, Y Yokota… - Journal of Veterinary …, 2009 - jstage.jst.go.jp
The prevalence of hepatitis E virus (HEV) infection in wild boars and pigs in Gunma Prefecture,
Japan, was serologically and genetically examined. The positive detection rates of anti-…