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Index by author

June 01, 2011; Volume 39,Issue 6

  1. D'agostino, Jaime

    1. Role of Intestinal Cytochrome P450 (P450) in Modulating the Bioavailability of Oral Lovastatin: Insights from Studies on the Intestinal Epithelium-Specific P450 Reductase Knockout Mouse
      Yi Zhu, Jaime D'Agostino and Qing-Yu Zhang
      Drug Metabolism and Disposition June 2011, 39 (6) 939-943; DOI: https://doi.org/10.1124/dmd.110.037861

  2. Day, Stephen

    1. Pharmacokinetics and Metabolism in Rats, Dogs, and Monkeys of the Cathepsin K Inhibitor Odanacatib: Demethylation of a Methylsulfonyl Moiety as a Major Metabolic Pathway
      Kelem Kassahun, W. Cameron Black, Deborah Nicoll-Griffith, Ian McIntosh, Nathalie Chauret, Stephen Day, Elizabeth Rosenberg and Kenneth Koeplinger
      Drug Metabolism and Disposition June 2011, 39 (6) 1079-1087; DOI: https://doi.org/10.1124/dmd.110.037184

  3. Debori, Yasuyuki

    1. Prediction of the Overall Renal Tubular Secretion and Hepatic Clearance of Anionic Drugs and a Renal Drug-Drug Interaction Involving Organic Anion Transporter 3 in Humans by In Vitro Uptake Experiments
      Takao Watanabe, Hiroyuki Kusuhara, Tomoko Watanabe, Yasuyuki Debori, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Brian W. Ogilvie, Andrew Parkinson, Zhuohan Hu and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2011, 39 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.110.036129

  4. Deese, Alan

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]GDC-0449 (Vismodegib), an Orally Active Hedgehog Pathway Inhibitor, in Rats and Dogs: A Unique Metabolic Pathway via Pyridine Ring Opening
      Qin Yue, Yung-Hsiang Chen, Teresa Mulder, Alan Deese, Ryan Takahashi, Patrick J. Rudewicz, Mark Reynolds, Eric Solon, Cornelis E. C. A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition June 2011, 39 (6) 952-965; DOI: https://doi.org/10.1124/dmd.110.037374

  5. Deng, Pan

    1. Identification of Amiodarone Metabolites in Human Bile by Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry
      Pan Deng, Tiangeng You, Xiaoyan Chen, Tao Yuan, Haihua Huang and Dafang Zhong
      Drug Metabolism and Disposition June 2011, 39 (6) 1058-1069; DOI: https://doi.org/10.1124/dmd.110.037671

  6. Denton, Rebecca

    1. Prediction of Human Renal Clearance from Preclinical Species for a Diverse Set of Drugs That Exhibit Both Active Secretion and Net Reabsorption
      Stuart W. Paine, Karelle Ménochet, Rebecca Denton, Dermot F. McGinnity and Robert J. Riley
      Drug Metabolism and Disposition June 2011, 39 (6) 1008-1013; DOI: https://doi.org/10.1124/dmd.110.037267

  7. Diffenderfer, Laura E.

    1. Substituted Imidazole of 5-Fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine Inactivates Cytochrome P450 2D6 by Protein Adduction
      Leslie D. Nagy, Catherine S. Mocny, Laura E. Diffenderfer, David J. Hsi, Brendan F. Butler, Evan J. Arthur, Kyle J. Fletke, Jairam R. Palamanda, Amin A. Nomeir and Laura Lowe Furge
      Drug Metabolism and Disposition June 2011, 39 (6) 974-983; DOI: https://doi.org/10.1124/dmd.110.037630

  8. Ding, Xinxin

    1. The Tissue-Specific Toxicity of Methimazole in the Mouse Olfactory Mucosa Is Partly Mediated through Target-Tissue Metabolic Activation by CYP2A5
      Fang Xie, Xin Zhou, Mary Beth Genter, Melissa Behr, Jun Gu and Xinxin Ding
      Drug Metabolism and Disposition June 2011, 39 (6) 947-951; DOI: https://doi.org/10.1124/dmd.110.037895

  9. Dong, Yafeng

    1. ATP-Binding Cassette Transporter Expression in Human Placenta as a Function of Pregnancy Condition
      Cifford W. Mason, Irina A. Buhimschi, Catalin S. Buhimschi, Yafeng Dong, Carl P. Weiner and Peter W. Swaan
      Drug Metabolism and Disposition June 2011, 39 (6) 1000-1007; DOI: https://doi.org/10.1124/dmd.111.038166
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