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Different Hydrolases Involved in Bioactivation of Prodrug-Type Angiotensin Receptor Blockers: Carboxymethylenebutenolidase and Carboxylesterase 1

Tomoko Ishizuka, Yasushi Yoshigae, Nobuyuki Murayama and Takashi Izumi
Drug Metabolism and Disposition August 14, 2013, dmd.113.053595; DOI: https://doi.org/10.1124/dmd.113.053595

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    Hydrolysis of p-nitrophenyl acetate (PNPA), clopidogrel, and CPT-11 by recombinant human CES1 and CES2

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