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Comparison of 19F-NMR and 14C measurements for the assessment of ADME of BYL719 (Alpelisib) in humans

Alexander D James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
Drug Metabolism and Disposition May 31, 2017, dmd.117.075424; DOI: https://doi.org/10.1124/dmd.117.075424

  • Data Supplement -

    Figure S1. Synthetic scheme for [14C]BYL719 (Alpelisib)

    Figure S2. Synthetic scheme (last 2 steps) for metabolite M4. Preceding steps are published in Furet et al, 2013.



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