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3-epi-18β-glycyrrhetinic acid or its glucuronide, the metabolites of glycyrrhizinic acid with individual differences, correlated with diagnostic maker for licorice-induced pseudoaldosteronism in humans

Ryota Sakoda, Kan'ichiro Ishiuchi, Tetsuhiro Yoshino, Yuna Tsunoo, Takao Namiki, Keiko Ogawa-Ochiai, Kiyoshi Minamizawa, Koichi Fukunaga, Kenji Watanabe and Toshiaki Makino
Drug Metabolism and Disposition September 16, 2024, DMD-AR-2024-001840; DOI: https://doi.org/10.1124/dmd.124.001840

Data Supplement

  • Supplemental Data -

    Supplemental Figure S1. Relationships between the serum and urine concentrations of glycyrrhizinic acid (GL) metabolites.

    Supplemental Figure S2. Relationships between each metabolite of glycyrrhizinic acid (GL) and pseudoaldosteronism (PsA) markers.

    Supplemental Table S1. Donor information of pooled human kidney microsome product shown in the package insert.

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