Table of Contents

Articles

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  Structure-Activity Relationship inO-Glucuronidation of Indolocarbazole Analogs

  Norihiro Takenaga, Mikio Ishii, Toshio Kamei and Toshio Yasumori

  Drug Metabolism and Disposition May 2002, 30 (5) 494-497; DOI: https://doi.org/10.1124/dmd.30.5.494
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  Carrier-Mediated Active Transport of a Novel Thromboxane A₂ Receptor Antagonist [2-(4-Chlorophenylsulfonylaminomethyl)indan-5-yl]acetate (Z-335) into Rat Liver

  Yoshihiro Kawabata, Shigeru Furuta, Yutaka Shinozaki, Tadashi Kurimoto and Ryuichiro Nishigaki

  Drug Metabolism and Disposition May 2002, 30 (5) 498-504; DOI: https://doi.org/10.1124/dmd.30.5.498
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  Glucuronidation of Statins in Animals and Humans: A Novel Mechanism of Statin Lactonization

  Thomayant Prueksaritanont, Raju Subramanian, Xiaojun Fang, Bennett Ma, Yue Qiu, Jiunn H. Lin, Paul G. Pearson and Thomas A. Baillie

  Drug Metabolism and Disposition May 2002, 30 (5) 505-512; DOI: https://doi.org/10.1124/dmd.30.5.505
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  Neotrofin Is Transported Out of Brain by a Saturable Mechanism: Possible Involvement of Multidrug Resistance and Monocarboxylic Acid Transporters

  Rongzi Yan and Eve M. Taylor

  Drug Metabolism and Disposition May 2002, 30 (5) 513-518; DOI: https://doi.org/10.1124/dmd.30.5.513
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  3-O-Methyldobutamine, a Major Metabolite of Dobutamine in Humans

  Maohe Yan, Leslie T. Webster and Jeffrey L. Blumer

  Drug Metabolism and Disposition May 2002, 30 (5) 519-524; DOI: https://doi.org/10.1124/dmd.30.5.519
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  Triethylenethiophosphoramide Is a Specific Inhibitor of Cytochrome P450 2B6: Implications for Cyclophosphamide Metabolism

  James M. Rae, Nadia V. Soukhova, David A. Flockhart and Zeruesenay Desta

  Drug Metabolism and Disposition May 2002, 30 (5) 525-530; DOI: https://doi.org/10.1124/dmd.30.5.525
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  Glucuronidation of the Dietary Fatty Acids, Phytanic Acid and Docosahexaenoic Acid, by Human UDP-Glucuronosyltransferases

  Joanna M. Little, Lisa Williams, Jing Xu and Anna Radominska-Pandya

  Drug Metabolism and Disposition May 2002, 30 (5) 531-533; DOI: https://doi.org/10.1124/dmd.30.5.531
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  Effects of Endogenous Steroids on CYP3A4-Mediated Drug Metabolism by Human Liver Microsomes

  Hiroyoshi Nakamura, Hiromitsu Nakasa, Itsuko Ishii, Noritaka Ariyoshi, Takashi Igarashi, Shigeru Ohmori and Mitsukazu Kitada

  Drug Metabolism and Disposition May 2002, 30 (5) 534-540; DOI: https://doi.org/10.1124/dmd.30.5.534
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  Human and Rodent Carboxylesterases: Immunorelatedness, Overlapping Substrate Specificity, Differential Sensitivity to Serine Enzyme Inhibitors, and Tumor-Related Expression

  Mingxing Xie, Dongfang Yang, Lan Liu, Bob Xue and Bingfang Yan

  Drug Metabolism and Disposition May 2002, 30 (5) 541-547; DOI: https://doi.org/10.1124/dmd.30.5.541
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  Expression of the Rat CYP2A3 Gene in Transgenic Mice

  Ting Su, Qing-Yu Zhang, Jianhua Zhang, Pam Swiatek and Xinxin Ding

  Drug Metabolism and Disposition May 2002, 30 (5) 548-552; DOI: https://doi.org/10.1124/dmd.30.5.548
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  The Metabolism and Excretion of Galantamine in Rats, Dogs, and Humans

  G. S. J. Mannens, C. A. W. Snel, J. Hendrickx, T. Verhaeghe, L. Le Jeune, W. Bode, L. van Beijsterveldt, K. Lavrijsen, J. Leempoels, N. Van Osselaer, A. Van Peer and W. Meuldermans

  Drug Metabolism and Disposition May 2002, 30 (5) 553-563; DOI: https://doi.org/10.1124/dmd.30.5.553
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  Induction of Human UDP-Glucuronosyltransferase UGT1A1 by Flavonoids—Structural Requirements

  U. Kristina Walle and Thomas Walle

  Drug Metabolism and Disposition May 2002, 30 (5) 564-569; DOI: https://doi.org/10.1124/dmd.30.5.564
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  Induction of CYP3A Expression by Dehydroepiandrosterone: Involvement of the Pregnane X Receptor

  Sharon L. Ripp, Jennifer L. Fitzpatrick, Jeffrey M. Peters and Russell A. Prough

  Drug Metabolism and Disposition May 2002, 30 (5) 570-575; DOI: https://doi.org/10.1124/dmd.30.5.570
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  Glucuronidation versus Oxidation of the Flavonoid Galangin by Human Liver Microsomes and Hepatocytes

  Yoko Otake, Faye Hsieh and Thomas Walle

  Drug Metabolism and Disposition May 2002, 30 (5) 576-581; DOI: https://doi.org/10.1124/dmd.30.5.576
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  Sulfation of Budesonide by Human Cytosolic Sulfotransferase, Dehydroepiandrosterone-Sulfotransferase (DHEA-ST)

  Connie A. Meloche, Vyas Sharma, Stellan Swedmark, Paul Andersson and Charles N. Falany

  Drug Metabolism and Disposition May 2002, 30 (5) 582-585; DOI: https://doi.org/10.1124/dmd.30.5.582
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  Intestinal Metabolism: The Role of Enzyme Localization in Phenol Metabolite Kinetics

  Prajakti A. Kothare and Cheryl L. Zimmerman

  Drug Metabolism and Disposition May 2002, 30 (5) 586-594; DOI: https://doi.org/10.1124/dmd.30.5.586
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  Characterization of Cytochrome P450 2D6.1 (CYP2D6.1), CYP2D6.2, and CYP2D6.17 Activities toward Model CYP2D6 Substrates Dextromethorphan, Bufuralol, and Debrisoquine

  Kenda A. Marcucci, Robin E. Pearce, Charles Crespi, Dorothy T. Steimel, J. Steven Leeder and Andrea Gaedigk

  Drug Metabolism and Disposition May 2002, 30 (5) 595-601; DOI: https://doi.org/10.1124/dmd.30.5.595
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  Metabolism of (+)- and (−)-Limonenes to Respective Carveols and Perillyl Alcohols by CYP2C9 and CYP2C19 in Human Liver Microsomes

  Mitsuo Miyazawa, Masaki Shindo and Tsutomu Shimada

  Drug Metabolism and Disposition May 2002, 30 (5) 602-607; DOI: https://doi.org/10.1124/dmd.30.5.602