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Research ArticleArticle

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

Ivan Nestorov, Ivelina Gueorguieva, Hannah M. Jones, Brian Houston and Malcolm Rowland
Drug Metabolism and Disposition March 2002, 30 (3) 276-282; DOI: https://doi.org/10.1124/dmd.30.3.276

Article Information

vol. 30 no. 3 276-282
DOI 
https://doi.org/10.1124/dmd.30.3.276
PubMed 
11854145
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 28, 2001
  • Accepted November 30, 2001
  • Published online March 1, 2002.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ivan Nestorov1,
  2. Ivelina Gueorguieva1,
  3. Hannah M. Jones1,
  4. Brian Houston1,2 and
  5. Malcolm Rowland1,2
  1. 1Centre for Applied Pharmacokinetic Research (I.N., I.G., H.M.J., B.H., M.R.) and 2School of Pharmacy and Pharmaceutical Sciences (B.H., M.R.), University of Manchester, Manchester, United Kingdom
  1. Ivelina Gueorguieva, Centre for Applied Pharmacokinetic Research School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Oxford Road, Manchester M13 9PL, United Kingdom. E-mail:ivelina.gueorguieva{at}man.ac.uk
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Research ArticleArticle

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

Ivan Nestorov, Ivelina Gueorguieva, Hannah M. Jones, Brian Houston and Malcolm Rowland
Drug Metabolism and Disposition March 1, 2002, 30 (3) 276-282; DOI: https://doi.org/10.1124/dmd.30.3.276
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