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Research ArticleArticle

IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER

Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
Drug Metabolism and Disposition April 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625

Article Information

vol. 34 no. 4 534-538
DOI 
https://doi.org/10.1124/dmd.105.007625
PubMed 
16415122
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 29, 2005
  • Accepted January 9, 2006
  • Published online March 21, 2006.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jean-Didier Marechal,
  2. Jinglei Yu,
  3. Simon Brown,
  4. Iouri Kapelioukh,
  5. Elaine M. Rankin,
  6. C. Roland Wolf,
  7. Gordon C. K. Roberts,
  8. Mark. J. I. Paine and
  9. Michael J. Sutcliffe
  1. Manchester Interdisciplinary Biocentre, School of Chemical Engineering and Analytical Science, University of Manchester, Manchester, United Kingdom (J.-D.M., M.J.S.); Biomedical Research Centre, University of Dundee, Ninewells Hospital & Medical School, Dundee, United Kingdom (J.Y., S.B., I.K., E.M.R., C.R.W., M.J.I.P.); and Department of Biochemistry, University of Leicester, Leicester, United Kingdom (G.C.K.R.)
  1. Address correspondence to:
    Professor Michael J. Sutcliffe, School of Chemical Engineering and Analytical Science, University of Manchester, The Mill, PO Box 88, Manchester, M60 1QD, UK. E-mail: michael.sutcliffe{at}manchester.ac.uk
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Research ArticleArticle

IN SILICO AND IN VITRO SCREENING FOR INHIBITION OF CYTOCHROME P450 CYP3A4 BY COMEDICATIONS COMMONLY USED BY PATIENTS WITH CANCER

Jean-Didier Marechal, Jinglei Yu, Simon Brown, Iouri Kapelioukh, Elaine M. Rankin, C. Roland Wolf, Gordon C. K. Roberts, Mark. J. I. Paine and Michael J. Sutcliffe
Drug Metabolism and Disposition April 1, 2006, 34 (4) 534-538; DOI: https://doi.org/10.1124/dmd.105.007625
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