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Research ArticleArticle

The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases

Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
Drug Metabolism and Disposition November 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731

Article Information

vol. 36 no. 11 2307-2315
DOI 
https://doi.org/10.1124/dmd.108.022731
PubMed 
18719240
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 5, 2008
  • Accepted August 18, 2008
  • Published online October 17, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Katriina Itäaho,
  2. Peter I. Mackenzie,
  3. Shin-ichi Ikushiro,
  4. John O. Miners and
  5. Moshe Finel
  1. Division of Pharmaceutical Chemistry (K.I.) and Center for Drug Research (M.F.), Faculty of Pharmacy, University of Helsinki, Helsinki, Finland; Department of Clinical Pharmacology, School of Medicine, Flinders University, Adelaide, South Australia, Australia (P.I.M., J.O.M.); and Department of Biotechnology, Toyama Prefectural University, Toyama, Japan (S.-i.I.)
  1. Address correspondence to:
    Moshe Finel, Faculty of Pharmacy, P.O. Box 56 (Viikinkaari 5), University of Helsinki, FIN-00014 Helsinki, Finland. E-mail: moshe.finel{at}helsinki.fi
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Research ArticleArticle

The Configuration of the 17-Hydroxy Group Variably Influences the Glucuronidation of β-Estradiol and Epiestradiol by Human UDP-Glucuronosyltransferases

Katriina Itäaho, Peter I. Mackenzie, Shin-ichi Ikushiro, John O. Miners and Moshe Finel
Drug Metabolism and Disposition November 1, 2008, 36 (11) 2307-2315; DOI: https://doi.org/10.1124/dmd.108.022731
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