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Research ArticleArticle

Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants

Youbin Tu, Rahul Deshmukh, Meena Sivaneri and Grazyna D. Szklarz
Drug Metabolism and Disposition November 2008, 36 (11) 2371-2380; DOI: https://doi.org/10.1124/dmd.108.022640

Article Information

vol. 36 no. 11 2371-2380
DOI 
https://doi.org/10.1124/dmd.108.022640
PubMed 
18703643
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 1, 2008
  • Accepted August 13, 2008
  • Published online October 17, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Youbin Tu,
  2. Rahul Deshmukh1,
  3. Meena Sivaneri and
  4. Grazyna D. Szklarz
  1. Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, Morgantown, West Virginia
  1. Address correspondence to:
    Dr. Grazyna D. Szklarz, Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, P.O. Box 9530, Morgantown, WV 26506-9530. E-mail: gszklarz{at}hsc.wvu.edu
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Research ArticleArticle

Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants

Youbin Tu, Rahul Deshmukh, Meena Sivaneri and Grazyna D. Szklarz
Drug Metabolism and Disposition November 1, 2008, 36 (11) 2371-2380; DOI: https://doi.org/10.1124/dmd.108.022640
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