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Research ArticleArticle

Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro

Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis
Drug Metabolism and Disposition March 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820

Article Information

vol. 36 no. 3 604-613
DOI 
https://doi.org/10.1124/dmd.107.018820
PubMed 
18094037
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 11, 2007
  • Accepted December 18, 2007
  • Published online February 22, 2008.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Esther G. van de Kerkhof,
  2. Inge A. M. de Graaf,
  3. Anna-Lena B. Ungell and
  4. Geny M. M. Groothuis
  1. Department of Pharmacokinetics and Drug Delivery, Groningen Research Institute for Pharmacy, University of Groningen, Groningen, The Netherlands (E.G.v.d.K., I.A.M.d.G., G.M.M.G.), and AstraZeneca DMPK and Bioanalytical Chemistry, Mölndal, Sweden (A.-L.B.U.)
  1. Address correspondence to:
    Dr. G. M. M. Groothuis, Department of Pharmacokinetics & Drug Delivery, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands. E-mail: g.m.m.groothuis{at}rug.nl
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Research ArticleArticle

Induction of Metabolism and Transport in Human Intestine: Validation of Precision-Cut Slices as a Tool to Study Induction of Drug Metabolism in Human Intestine in Vitro

Esther G. van de Kerkhof, Inge A. M. de Graaf, Anna-Lena B. Ungell and Geny M. M. Groothuis
Drug Metabolism and Disposition March 1, 2008, 36 (3) 604-613; DOI: https://doi.org/10.1124/dmd.107.018820
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