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Index by author

June 01, 2011; Volume 39,Issue 6

  1. Chan, Eric Chun Yong

    1. Metabolic Intermediate Complex Formation of Human Cytochrome P450 3A4 by Lapatinib
      Hideo Takakusa, Michelle D. Wahlin, Chunsheng Zhao, Kelsey L. Hanson, Lee Sun New, Eric Chun Yong Chan and Sidney D. Nelson
      Drug Metabolism and Disposition June 2011, 39 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.110.037531

  2. Chauret, Nathalie

    1. Pharmacokinetics and Metabolism in Rats, Dogs, and Monkeys of the Cathepsin K Inhibitor Odanacatib: Demethylation of a Methylsulfonyl Moiety as a Major Metabolic Pathway
      Kelem Kassahun, W. Cameron Black, Deborah Nicoll-Griffith, Ian McIntosh, Nathalie Chauret, Stephen Day, Elizabeth Rosenberg and Kenneth Koeplinger
      Drug Metabolism and Disposition June 2011, 39 (6) 1079-1087; DOI: https://doi.org/10.1124/dmd.110.037184

  3. Chen, Xiaoyan

    1. Identification of Amiodarone Metabolites in Human Bile by Ultraperformance Liquid Chromatography/Quadrupole Time-of-Flight Mass Spectrometry
      Pan Deng, Tiangeng You, Xiaoyan Chen, Tao Yuan, Haihua Huang and Dafang Zhong
      Drug Metabolism and Disposition June 2011, 39 (6) 1058-1069; DOI: https://doi.org/10.1124/dmd.110.037671

  4. Chen, Yung-Hsiang

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]GDC-0449 (Vismodegib), an Orally Active Hedgehog Pathway Inhibitor, in Rats and Dogs: A Unique Metabolic Pathway via Pyridine Ring Opening
      Qin Yue, Yung-Hsiang Chen, Teresa Mulder, Alan Deese, Ryan Takahashi, Patrick J. Rudewicz, Mark Reynolds, Eric Solon, Cornelis E. C. A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition June 2011, 39 (6) 952-965; DOI: https://doi.org/10.1124/dmd.110.037374

  5. Collier, Ann C.

    1. Complex Drug Interactions of HIV Protease Inhibitors 1: Inactivation, Induction, and Inhibition of Cytochrome P450 3A by Ritonavir or Nelfinavir
      Brian J. Kirby, Ann C. Collier, Evan D. Kharasch, Dale Whittington, Kenneth E. Thummel and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2011, 39 (6) 1070-1078; DOI: https://doi.org/10.1124/dmd.110.037523

  6. Czendlik, C.

    1. Pharmacokinetics of the Monohydroxy Derivative of Oxcarbazepine and Its Enantiomers after a Single Intravenous Dose Given as Racemate Compared with a Single Oral Dose of Oxcarbazepine
      G. Flesch, C. Czendlik, D. Renard and P. Lloyd
      Drug Metabolism and Disposition June 2011, 39 (6) 1103-1110; DOI: https://doi.org/10.1124/dmd.109.030593

  7. D'agostino, Jaime

    1. Role of Intestinal Cytochrome P450 (P450) in Modulating the Bioavailability of Oral Lovastatin: Insights from Studies on the Intestinal Epithelium-Specific P450 Reductase Knockout Mouse
      Yi Zhu, Jaime D'Agostino and Qing-Yu Zhang
      Drug Metabolism and Disposition June 2011, 39 (6) 939-943; DOI: https://doi.org/10.1124/dmd.110.037861

  8. Day, Stephen

    1. Pharmacokinetics and Metabolism in Rats, Dogs, and Monkeys of the Cathepsin K Inhibitor Odanacatib: Demethylation of a Methylsulfonyl Moiety as a Major Metabolic Pathway
      Kelem Kassahun, W. Cameron Black, Deborah Nicoll-Griffith, Ian McIntosh, Nathalie Chauret, Stephen Day, Elizabeth Rosenberg and Kenneth Koeplinger
      Drug Metabolism and Disposition June 2011, 39 (6) 1079-1087; DOI: https://doi.org/10.1124/dmd.110.037184

  9. Debori, Yasuyuki

    1. Prediction of the Overall Renal Tubular Secretion and Hepatic Clearance of Anionic Drugs and a Renal Drug-Drug Interaction Involving Organic Anion Transporter 3 in Humans by In Vitro Uptake Experiments
      Takao Watanabe, Hiroyuki Kusuhara, Tomoko Watanabe, Yasuyuki Debori, Kazuya Maeda, Tsunenori Kondo, Hideki Nakayama, Shigeru Horita, Brian W. Ogilvie, Andrew Parkinson, Zhuohan Hu and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2011, 39 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.110.036129

  10. Deese, Alan

    1. Absorption, Distribution, Metabolism, and Excretion of [14C]GDC-0449 (Vismodegib), an Orally Active Hedgehog Pathway Inhibitor, in Rats and Dogs: A Unique Metabolic Pathway via Pyridine Ring Opening
      Qin Yue, Yung-Hsiang Chen, Teresa Mulder, Alan Deese, Ryan Takahashi, Patrick J. Rudewicz, Mark Reynolds, Eric Solon, Cornelis E. C. A. Hop, Harvey Wong and S. Cyrus Khojasteh
      Drug Metabolism and Disposition June 2011, 39 (6) 952-965; DOI: https://doi.org/10.1124/dmd.110.037374
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