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Hepatic, Intestinal, Renal, and Plasma Hydrolysis of Prodrugs in Human, Cynomolgus Monkey, Dog, and Rat: Implications for In Vitro–In Vivo Extrapolation of Clearance of Prodrugs

Haruka Nishimuta, J. Brian Houston and Aleksandra Galetin
Drug Metabolism and Disposition September 2014, 42 (9) 1522-1531; DOI: https://doi.org/10.1124/dmd.114.057372
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Species and System Differences in Hydrolysis Activities

Haruka Nishimuta, J. Brian Houston and Aleksandra Galetin
Drug Metabolism and Disposition September 1, 2014, 42 (9) 1522-1531; DOI: https://doi.org/10.1124/dmd.114.057372
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