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Research ArticleArticle

Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model

Shinji Yamazaki, Theodore R. Johnson and Bill J. Smith
Drug Metabolism and Disposition October 2015, 43 (10) 1417-1429; DOI: https://doi.org/10.1124/dmd.115.064618

Article Information

vol. 43 no. 10 1417-1429
DOI 
https://doi.org/10.1124/dmd.115.064618
PubMed 
26180127
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 31, 2015
  • Accepted July 15, 2015
  • Published online August 24, 2015.

Article Versions

Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Shinji Yamazaki,
  2. Theodore R. Johnson, and
  3. Bill J. Smith1
  1. Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, San Diego, California
  1. Address correspondence to:
    Dr. Shinji Yamazaki, Pharmacokinetics, Dynamics and Metabolism, La Jolla Laboratories, Pfizer Worldwide Research and Development, 10777 Science Center Drive, San Diego, CA 92121. E-mail: shinji.yamazaki{at}pfizer.com
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Research ArticleArticle

Prediction of Crizotinib Drug-Drug Interactions

Shinji Yamazaki, Theodore R. Johnson and Bill J. Smith
Drug Metabolism and Disposition October 1, 2015, 43 (10) 1417-1429; DOI: https://doi.org/10.1124/dmd.115.064618
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