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Microvilli Morphology Can Affect Efflux Active P-Glycoprotein in Confluent MDCKII -hMDR1-NKI and Caco-2 Cell Monolayers

Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
Drug Metabolism and Disposition February 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157

Article Information

vol. 45 no. 2 145-151
DOI 
https://doi.org/10.1124/dmd.116.072157
PubMed 
27856525
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 21, 2016
  • Accepted November 7, 2016
  • Published online January 12, 2017.

Article Versions

Copyright & Usage 
Copyright © 2017 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Zhou Meng,
  2. Sylvain Le Marchand,
  3. Deep Agnani,
  4. Matthew Szapacs,
  5. Harma Ellens, and
  6. Joe Bentz
  1. Department of Biology, Drexel University, Philadelphia, Pennsylvania (Z.M., S.L.M., D.A., J.B.); and Drug Metabolism and Pharmacokinetics, GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania (Z.M., M.S., H.E.)
  1. Address correspondence to:
    Dr. Joe Bentz, Drexel University, Biology Department, 3245 Chestnut Street, Philadelphia, PA 19104. E-mail: bentzj{at}drexel.edu
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Research ArticleArticle

Microvilli Morphology Affects P-gp Efflux Activity

Zhou Meng, Sylvain Le Marchand, Deep Agnani, Matthew Szapacs, Harma Ellens and Joe Bentz
Drug Metabolism and Disposition February 1, 2017, 45 (2) 145-151; DOI: https://doi.org/10.1124/dmd.116.072157
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