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Index by author

June 01, 2022; Volume 50,Issue 6

  1. Maclauchlin, Chris

    1. The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of <em>N</em>-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Open Access
      The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher Brown, Elena Castellanos-Rizaldos, Klaus Charisse, Saeho Chong, Joseph Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale Guenther, Bahru Habtemariam, Vasant Jadhav, Maja Janas, Muthusamy Jayaraman, Jeffrey Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel Robbie, Karyn Schmidt, Peter Smith, Christopher Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev and Jing-Tao Wu
      Drug Metabolism and Disposition June 2022, 50 (6) 781-797; DOI: https://doi.org/10.1124/dmd.121.000428

  2. Maier, Martin

    1. The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of <em>N</em>-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Open Access
      The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher Brown, Elena Castellanos-Rizaldos, Klaus Charisse, Saeho Chong, Joseph Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale Guenther, Bahru Habtemariam, Vasant Jadhav, Maja Janas, Muthusamy Jayaraman, Jeffrey Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel Robbie, Karyn Schmidt, Peter Smith, Christopher Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev and Jing-Tao Wu
      Drug Metabolism and Disposition June 2022, 50 (6) 781-797; DOI: https://doi.org/10.1124/dmd.121.000428

  3. Manautou, José E.

    1. Adverse Drug Reactions and Toxicity of the Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
      Feryal Alhamadani, Kristy Zhang, Rajvi Parikh, Hangyu Wu, Theodore P. Rasmussen, Raman Bahal, Xiao-bo Zhong and José E. Manautou
      Drug Metabolism and Disposition June 2022, 50 (6) 879-887; DOI: https://doi.org/10.1124/dmd.121.000418
    2. Absorption, Distribution, Metabolism, and Excretion of US Food and Drug Administration–Approved Antisense Oligonucleotide Drugs
      Julia M. Migliorati, Sunna Liu, Anna Liu, Anagha Gogate, Sreenidhi Nair, Raman Bahal, Theodore P. Rasmussen, José E. Manautou and Xiao-bo Zhong
      Drug Metabolism and Disposition June 2022, 50 (6) 888-897; DOI: https://doi.org/10.1124/dmd.121.000417

  4. Manoharan, Muthiah

    1. The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of <em>N</em>-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Open Access
      The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher Brown, Elena Castellanos-Rizaldos, Klaus Charisse, Saeho Chong, Joseph Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale Guenther, Bahru Habtemariam, Vasant Jadhav, Maja Janas, Muthusamy Jayaraman, Jeffrey Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel Robbie, Karyn Schmidt, Peter Smith, Christopher Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev and Jing-Tao Wu
      Drug Metabolism and Disposition June 2022, 50 (6) 781-797; DOI: https://doi.org/10.1124/dmd.121.000428

  5. Martin, Jennifer A.

    1. Absorption, Distribution, Metabolism, and Excretion of Therapeutic Proteins: Current Industry Practices and Future Perspectives
      Jayaprakasam Bolleddula, Kevin Brady, Gerard Bruin, Anthony Lee, Jennifer A. Martin, Markus Walles, Keyang Xu, Tong-Yuan Yang, Xiaochun Zhu and Hongbin Yu
      Drug Metabolism and Disposition June 2022, 50 (6) 837-845; DOI: https://doi.org/10.1124/dmd.121.000461

  6. Matsumoto, Kazuaki

    1. Augmented Clearance of Nivolumab Is Associated with Renal Functions in Chronic Renal Disease Model Rats
      Augmented Clearance of Nivolumab Is Associated with Renal Functions in Chronic Renal Disease Model Rats
      Kazuaki Taguchi, Yukitaka Hayashi, Mayu Ohuchi, Hotaka Yamada, Shigehiro Yagishita, Yuki Enoki, Kazuaki Matsumoto and Akinobu Hamada
      Drug Metabolism and Disposition June 2022, 50 (6) 822-826; DOI: https://doi.org/10.1124/dmd.121.000520

  7. Mcdougall, Robin

    1. The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of <em>N</em>-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Open Access
      The Nonclinical Disposition and Pharmacokinetic/Pharmacodynamic Properties of N-Acetylgalactosamine–Conjugated Small Interfering RNA Are Highly Predictable and Build Confidence in Translation to Human
      Robin McDougall, Diane Ramsden, Sagar Agarwal, Saket Agarwal, Krishna Aluri, Michael Arciprete, Christopher Brown, Elena Castellanos-Rizaldos, Klaus Charisse, Saeho Chong, Joseph Cichocki, Kevin Fitzgerald, Varun Goel, Yongli Gu, Dale Guenther, Bahru Habtemariam, Vasant Jadhav, Maja Janas, Muthusamy Jayaraman, Jeffrey Kurz, Jing Li, Ju Liu, Xiumin Liu, Steven Liou, Chris Maclauchlin, Martin Maier, Muthiah Manoharan, Jayaprakash K. Nair, Gabriel Robbie, Karyn Schmidt, Peter Smith, Christopher Theile, Akshay Vaishnaw, Scott Waldron, Yuanxin Xu, Xuemei Zhang, Ivan Zlatev and Jing-Tao Wu
      Drug Metabolism and Disposition June 2022, 50 (6) 781-797; DOI: https://doi.org/10.1124/dmd.121.000428

  8. Meng, Jian

    1. Mechanistic Study on the Species Differences in Excretion Pathway of HR011303 in Humans and Rats
      Zitao Guo, Mengling Liu, Jian Meng, Yaru Xue, Qi Huang, Yuandong Zheng, Yali Wu, Zhendong Chen, Jinghua Yu, Dafang Zhong, Guangze Li, Xiaoyan Chen and Xingxing Diao
      Drug Metabolism and Disposition June 2022, 50 (6) 809-818; DOI: https://doi.org/10.1124/dmd.121.000582

  9. Miao, Jia

    1. Reevaluate In Vitro CYP3A Index Reactions of Benzodiazepines and Steroids between Humans and Dogs
      QingLiang Wu, YiTing Hu, CuiTong Wang, Wei Wei, LanLan Gui, WuShuang Zeng, Changxiao Liu, Wei Jia, Jia Miao and Ke Lan
      Drug Metabolism and Disposition June 2022, 50 (6) 741-749; DOI: https://doi.org/10.1124/dmd.122.000864

  10. Miao, Liyan

    1. Pharmacokinetics, Mass Balance, and Metabolism of the Novel Urate Transporter 1 Inhibitor [14C]HR011303 in Humans: Metabolism Is Mediated Predominantly by UDP-Glucuronosyltransferase
      Yuandong Zheng, Hua Zhang, Mengling Liu, Guangze Li, Sheng Ma, Zhe Zhang, Hongda Lin, Yan Zhan, Zhendong Chen, Dafang Zhong, Liyan Miao and Xingxing Diao
      Drug Metabolism and Disposition June 2022, 50 (6) 798-808; DOI: https://doi.org/10.1124/dmd.121.000581
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