Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice

Yury Kapelyukh; Colin James Henderson; Nico Scheer; Anja Rode; Charles Roland Wolf

doi:10.1124/dmd.119.087718

Research ArticleArticle

Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice

Yury Kapelyukh, Colin James Henderson, Nico Scheer, Anja Rode and Charles Roland Wolf

Drug Metabolism and Disposition May 30, 2019, dmd.119.087718; DOI: https://doi.org/10.1124/dmd.119.087718

Yury Kapelyukh

1 School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, UK;

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Colin James Henderson

1 School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, UK;

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ORCID record for Colin James Henderson

Nico Scheer

2 FH Aachen, University of Applied Sciences, Heinrich-Mussmann-Str.1, 52428 Juelich, Germany;

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Anja Rode

3 F. Hoffmann-La Roche, Grenzacherstrasse 1244070 Basel, Switzerland

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Charles Roland Wolf

1 School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, UK;

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For correspondence: c.r.wolf@dundee.ac.uk

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Drug Metabolism and Disposition

Vol. 52, Issue 12

1 Dec 2024

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Research ArticleArticle

Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice

Yury Kapelyukh, Colin James Henderson, Nico Scheer, Anja Rode and Charles Roland Wolf

Drug Metabolism and Disposition May 30, 2019, dmd.119.087718; DOI: https://doi.org/10.1124/dmd.119.087718

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Research ArticleArticle

Defining the contribution of CYP1A1 and CYP1A2 to drug metabolism using humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 KO mice

Yury Kapelyukh, Colin James Henderson, Nico Scheer, Anja Rode and Charles Roland Wolf

Drug Metabolism and Disposition May 30, 2019, dmd.119.087718; DOI: https://doi.org/10.1124/dmd.119.087718

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