UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES

Aleksandra Galetin; Caroline Brown; David Hallifax; Kiyomi Ito; J. Brian Houston

doi:10.1124/dmd.104.000844

Research ArticleArticle

UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES

Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston

Drug Metabolism and Disposition December 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

Aleksandra Galetin

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Caroline Brown

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David Hallifax

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Kiyomi Ito

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J. Brian Houston

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Drug Metabolism and Disposition

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1 Dec 2004

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Research ArticleArticle

UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES

Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston

Drug Metabolism and Disposition December 1, 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

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Research ArticleArticle

UTILITY OF RECOMBINANT ENZYME KINETICS IN PREDICTION OF HUMAN CLEARANCE: IMPACT OF VARIABILITY, CYP3A5, AND CYP2C19 ON CYP3A4 PROBE SUBSTRATES

Aleksandra Galetin, Caroline Brown, David Hallifax, Kiyomi Ito and J. Brian Houston

Drug Metabolism and Disposition December 1, 2004, 32 (12) 1411-1420; DOI: https://doi.org/10.1124/dmd.104.000844

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