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Research ArticleArticle

UDP-GLUCURONOSYLTRANSFERASE 2B7 IS THE MAJOR ENZYME RESPONSIBLE FOR GEMCABENE GLUCURONIDATION IN HUMAN LIVER MICROSOMES

Jonathan N. Bauman, Theunis C. Goosen, Meera Tugnait, Vincent Peterkin, Susan I. Hurst, Lee C. Menning, Mark Milad, Michael H. Court and J. Andrew Williams
Drug Metabolism and Disposition September 2005, 33 (9) 1349-1354; DOI: https://doi.org/10.1124/dmd.105.005108

Article Information

vol. 33 no. 9 1349-1354
DOI 
https://doi.org/10.1124/dmd.105.005108
PubMed 
15980101
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 8, 2005
  • Accepted June 17, 2005
  • Published online August 19, 2005.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jonathan N. Bauman,
  2. Theunis C. Goosen,
  3. Meera Tugnait,
  4. Vincent Peterkin,
  5. Susan I. Hurst,
  6. Lee C. Menning,
  7. Mark Milad,
  8. Michael H. Court and
  9. J. Andrew Williams
  1. Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, Ann Arbor, Michigan (J.N.B., T.C.G., M.T., V.P., S.I.H., L.C.M., M.M., J.A.W.) and Department of Pharmacology & Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts (M.H.C.)
  1. Address correspondence to:
    Jonathan N. Bauman, Department of Pharmacokinetics, Dynamics and Metabolism, Pfizer Global Research and Development, 2800 Plymouth Rd., Ann Arbor, MI 48105. E-mail: jonathan.bauman{at}pfizer.com
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Research ArticleArticle

UDP-GLUCURONOSYLTRANSFERASE 2B7 IS THE MAJOR ENZYME RESPONSIBLE FOR GEMCABENE GLUCURONIDATION IN HUMAN LIVER MICROSOMES

Jonathan N. Bauman, Theunis C. Goosen, Meera Tugnait, Vincent Peterkin, Susan I. Hurst, Lee C. Menning, Mark Milad, Michael H. Court and J. Andrew Williams
Drug Metabolism and Disposition September 1, 2005, 33 (9) 1349-1354; DOI: https://doi.org/10.1124/dmd.105.005108
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