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Research ArticleArticle

Up-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in Pregnancy

Huiqing Chen, Kyunghee Yang, Suyoung Choi, James H. Fischer and Hyunyoung Jeong
Drug Metabolism and Disposition September 2009, 37 (9) 1841-1847; DOI: https://doi.org/10.1124/dmd.109.026609

Article Information

vol. 37 no. 9 1841-1847
DOI 
https://doi.org/10.1124/dmd.109.026609
PubMed 
19546240
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Accepted June 18, 2009
  • Received January 7, 2009
  • Published online August 19, 2009.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Huiqing Chen1,
  2. Kyunghee Yang,
  3. Suyoung Choi,
  4. James H. Fischer and
  5. Hyunyoung Jeong
  1. Department of Pharmacy Practice (H.C., K.Y., J.H.F., H.J.), Center for Pharmaceutical Biotechnology (S.C.), and Department of Biopharmaceutical Sciences (H.J.), College of Pharmacy, University of Illinois at Chicago, Chicago, Illinois
  1. Address correspondence to:
    Dr. Hyunyoung Jeong, Department of Pharmacy Practice (MC 886), College of Pharmacy, University of Illinois at Chicago, 833 S. Wood St., Chicago, IL 60612. E-mail: yjeong{at}uic.edu
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Research ArticleArticle

Up-Regulation of UDP-Glucuronosyltransferase (UGT) 1A4 by 17β-Estradiol: A Potential Mechanism of Increased Lamotrigine Elimination in Pregnancy

Huiqing Chen, Kyunghee Yang, Suyoung Choi, James H. Fischer and Hyunyoung Jeong
Drug Metabolism and Disposition September 1, 2009, 37 (9) 1841-1847; DOI: https://doi.org/10.1124/dmd.109.026609
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