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Research ArticleArticle

Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite

Miroslav Dostalek, Michael H. Court, Suwagmani Hazarika and Fatemeh Akhlaghi
Drug Metabolism and Disposition March 2011, 39 (3) 448-455; DOI: https://doi.org/10.1124/dmd.110.036608

Article Information

vol. 39 no. 3 448-455
DOI 
https://doi.org/10.1124/dmd.110.036608
PubMed 
21123165
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 2, 2010
  • Accepted December 1, 2010
  • Published online February 17, 2011.

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Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Miroslav Dostalek,
  2. Michael H. Court,
  3. Suwagmani Hazarika and
  4. Fatemeh Akhlaghi
  1. Department of Biomedical and Pharmaceutical Sciences, College of Pharmacy, University of Rhode Island, Kingston, Rhode Island (M.D., F.A.); and Comparative and Molecular Pharmacogenomics Laboratory, Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine, Boston, Massachusetts (M.H.C., S.H.)
  1. Address correspondence to:
    Dr. Fatemeh Akhlaghi, Clinical Pharmacokinetics Research Laboratory and Center for Pharmacogenomics and Molecular Therapy, University of Rhode Island, 125 Fogarty Hall, 41 Lower College Road, Kingston, RI 02881. E-mail: fatemeh{at}uri.edu
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Research ArticleArticle

Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite

Miroslav Dostalek, Michael H. Court, Suwagmani Hazarika and Fatemeh Akhlaghi
Drug Metabolism and Disposition March 1, 2011, 39 (3) 448-455; DOI: https://doi.org/10.1124/dmd.110.036608
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