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Role of Intestinal Cytochrome P450 (P450) in Modulating the Bioavailability of Oral Lovastatin: Insights from Studies on the Intestinal Epithelium-Specific P450 Reductase Knockout Mouse

Yi Zhu, Jaime D'Agostino and Qing-Yu Zhang
Drug Metabolism and Disposition June 2011, 39 (6) 939-943; DOI: https://doi.org/10.1124/dmd.110.037861

Article Information

vol. 39 no. 6 939-943
DOI 
https://doi.org/10.1124/dmd.110.037861
PubMed 
21349922
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 17, 2010
  • Accepted February 24, 2011
  • Published online May 16, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yi Zhu,
  2. Jaime D'Agostino and
  3. Qing-Yu Zhang
  1. Laboratory of Molecular Toxicology, Division of Environmental Health Sciences, Wadsworth Center, New York State Department of Health, and School of Public Health, State University of New York at Albany, New York
  1. Address correspondence to:
    Dr. Qing-Yu Zhang, Wadsworth Center, New York State Department of Health, Empire State Plaza, Box 509, Albany, NY 12201-0509. E-mail: zhangq{at}wadsworth.org
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Rapid CommunicationShort Communication

Role of Intestinal Cytochrome P450 (P450) in Modulating the Bioavailability of Oral Lovastatin: Insights from Studies on the Intestinal Epithelium-Specific P450 Reductase Knockout Mouse

Yi Zhu, Jaime D'Agostino and Qing-Yu Zhang
Drug Metabolism and Disposition June 1, 2011, 39 (6) 939-943; DOI: https://doi.org/10.1124/dmd.110.037861
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