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Effects of Ketamine on Human UDP-Glucuronosyltransferases In Vitro Predict Potential Drug-Drug Interactions Arising from Ketamine Inhibition of Codeine and Morphine Glucuronidation

Verawan Uchaipichat, Pritsana Raungrut, Nuy Chau, Benjamas Janchawee, Allan M. Evans and John O. Miners
Drug Metabolism and Disposition August 2011, 39 (8) 1324-1328; DOI: https://doi.org/10.1124/dmd.111.039727

Article Information

vol. 39 no. 8 1324-1328
DOI 
https://doi.org/10.1124/dmd.111.039727
PubMed 
21551257
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 24, 2011
  • Accepted May 6, 2011
  • Published online July 18, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Verawan Uchaipichat,
  2. Pritsana Raungrut,
  3. Nuy Chau,
  4. Benjamas Janchawee,
  5. Allan M. Evans and
  6. John O. Miners
  1. Department of Clinical Pharmacology, Flinders University School of Medicine, Adelaide, Australia (V.U., P.R., N.C., J.O.M.); Faculty of Pharmaceutical Science, Khon Kaen University, Khon Kaen, Thailand (V.U.); Department of Biomedical Sciences, Prince of Songkla University, Hat Yai, Thailand (P.R., B.J.); School of Pharmacy and Medical Sciences, University of South Australia, Adelaide, Australia (A.M.E.)
  1. Address correspondence to:
    Professor John O. Miners, Department of Clinical Pharmacology, Flinders University School of Medicine, Flinders Medical Centre, Bedford Park, SA 5042, Australia. E-mail: john.miners{at}flinders.edu.au
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Rapid CommunicationShort Communication

Effects of Ketamine on Human UDP-Glucuronosyltransferases In Vitro Predict Potential Drug-Drug Interactions Arising from Ketamine Inhibition of Codeine and Morphine Glucuronidation

Verawan Uchaipichat, Pritsana Raungrut, Nuy Chau, Benjamas Janchawee, Allan M. Evans and John O. Miners
Drug Metabolism and Disposition August 1, 2011, 39 (8) 1324-1328; DOI: https://doi.org/10.1124/dmd.111.039727
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