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In Vitro Hepatotoxicity and Cytochrome P450 Induction and Inhibition Characteristics of Carnosic Acid, a Dietary Supplement with Antiadipogenic Properties

Leslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. Lin
Drug Metabolism and Disposition July 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909

Article Information

vol. 40 no. 7 1263-1267
DOI 
https://doi.org/10.1124/dmd.112.044909
PubMed 
22531045
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 1, 2012
  • Accepted April 20, 2012
  • Published online June 20, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Leslie J. Dickmann,
  2. Brooke M. VandenBrink and
  3. Yvonne S. Lin
  1. Biochemistry and Biophysics Group, Department of Pharmacokinetics and Drug Metabolism, Amgen Inc., Seattle, Washington (L.J.D., B.M.V.); and Department of Pharmaceutics, University of Washington, Seattle, Washington (Y.S.L.)
  1. Address correspondence to:
    Leslie J. Dickmann, 1201 Amgen Court W., Seattle, WA 98119. E-mail: ldickman{at}amgen.com
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Rapid CommunicationShort Communication

TOXICITY AND P450 INDUCTION AND INHIBITION BY CARNOSIC ACID

Leslie J. Dickmann, Brooke M. VandenBrink and Yvonne S. Lin
Drug Metabolism and Disposition July 1, 2012, 40 (7) 1263-1267; DOI: https://doi.org/10.1124/dmd.112.044909
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