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Research ArticleSpecial Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems

Utility of In Vitro Systems and Preclinical Data for the Prediction of Human Intestinal First-Pass Metabolism during Drug Discovery and Preclinical Development

Fredrik H. Karlsson, Salim Bouchene, Constanze Hilgendorf, Hugues Dolgos and Sheila Annie Peters
Drug Metabolism and Disposition December 2013, 41 (12) 2033-2046; DOI: https://doi.org/10.1124/dmd.113.051664
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Research ArticleSpecial Section on Prediction of Human Pharmacokinetic Parameters from In Vitro Systems

Prediction of Human Intestinal First-Pass Metabolism

Fredrik H. Karlsson, Salim Bouchene, Constanze Hilgendorf, Hugues Dolgos and Sheila Annie Peters
Drug Metabolism and Disposition December 1, 2013, 41 (12) 2033-2046; DOI: https://doi.org/10.1124/dmd.113.051664
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