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History
- Received November 20, 2012
- Accepted March 1, 2013
- Published online April 15, 2013.
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- Earlier version (March 1, 2013 - 11:36).
- You are viewing the most recent version of this article.
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Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics
Author Information
- Cho-Ming Loi,
- Dennis A. Smith, and
- Deepak Dalvie
- Pharmacokinetics, Dynamics, and Metabolism, Pfizer Worldwide Research and Development, San Diego, California (C.-M.L., D.D.); and Department of Chemistry, University of Capetown, South Africa and Institute of Translational Medicine, University of Liverpool, United Kingdom (D.A.S.)
- Address correspondence to:
Cho-Ming Loi, Pfizer, Inc., 10646 Science Center Drive, San Diego, CA 92121. E-mail: cho-ming.loi{at}pfizer.com
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- Theoretical Considerations of Determining In Vivo Metabolite Exposure
- Secondary or Primary Amines as Metabolites
- Alcohols and Ketones as Metabolites
- Arenol Metabolites
- S- and N-Oxides Metabolites
- Carboxylic Acid Metabolites
- Novel Metabolites
- Theoretical Considerations: Which Factors Appear Dominant?
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