Research ArticleArticle
Metabolite Kinetics: The Segregated Flow Model for Intestinal and Whole Body Physiologically Based Pharmacokinetic Modeling to Describe Intestinal and Hepatic Glucuronidation of Morphine in Rats In Vivo
Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
Drug Metabolism and Disposition July 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
Qi Joy Yang
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Jianghong Fan
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Shu Chen
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Lutan Liu
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
Huadong Sun
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
K. Sandy Pang
Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada
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Research ArticleArticle
Segregated Flow Model for Intestinal Morphine Glucuronidation
Qi Joy Yang, Jianghong Fan, Shu Chen, Lutan Liu, Huadong Sun and K. Sandy Pang
Drug Metabolism and Disposition July 1, 2016, 44 (7) 1123-1138; DOI: https://doi.org/10.1124/dmd.116.069542
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