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Carfilzomib Is Not an Appropriate Payload of Antibody-Drug Conjugates Due to Rapid Inactivation by Lysosomal Enzymes

Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
Drug Metabolism and Disposition August 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595
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Carfilzomib as an Inactive ADC Payload

Yong Ma, Josefa Dela Cruz-Chuh, S. Cyrus Khojasteh, Peter S. Dragovich, Thomas H. Pillow and Donglu Zhang
Drug Metabolism and Disposition August 1, 2019, 47 (8) 884-889; DOI: https://doi.org/10.1124/dmd.119.086595
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