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Uncovering the Impact of COVID-19 Mediated Bidirectional Dysregulation of CYP3A4 on Systemic and Pulmonary Drug Concentrations Using Physiologically Based Pharmacokinetic Modeling

Chukwunonso K. Nwabufo
Drug Metabolism and Disposition October 29, 2024, DMD-AR-2024-001893; DOI: https://doi.org/10.1124/dmd.124.001893

Article Information

DMD-AR-2024-001893
DOI 
https://doi.org/10.1124/dmd.124.001893
PubMed 
39472079
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Published online October 29, 2024.
Copyright & Usage 
© 2024 The Authors. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited and is not used for commercial purposes.

Author Information

  1. Chukwunonso K. Nwabufo1,*
  1. 1Pharmaceutical Sciences, University of Toronto, Canada
  1. ↵* Corresponding Author:
    Chukwunonso K. Nwabufo, Pharmaceutical Sciences, University of Toronto, 144 College Street, Toronto, M5S3M2, Canada. E-mail: Chukwunonso.nwabufo{at}mail.utoronto.ca

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Impact of COVID-19 on Intercompartmental Drug Concentrations

Chukwunonso K. Nwabufo
Drug Metabolism and Disposition October 29, 2024, DMD-AR-2024-001893; DOI: https://doi.org/10.1124/dmd.124.001893
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