Advertisement
Research ArticleArticle

Metabolism and Excretion of 6-Chloro-9-(4-methoxy-3,5-dimethylpyridin-2-ylmethyl)-9H-purin-2-ylamine, an HSP90 Inhibitor, in Rats and Dogs and Assessment of Its Metabolic Profile in Plasma of Humans

Lin Xu, Caroline Woodward, Jing Dai and Chandra Prakash
Drug Metabolism and Disposition December 2013, 41 (12) 2133-2147; DOI: https://doi.org/10.1124/dmd.113.054023

Article Information

vol. 41 no. 12 2133-2147
DOI 
https://doi.org/10.1124/dmd.113.054023
PubMed 
24046333
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 12, 2013
  • Accepted September 17, 2013
  • Published online November 14, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lin Xu,
  2. Caroline Woodward1,
  3. Jing Dai, and
  4. Chandra Prakash
  1. Drug Metabolism and Pharmacokinetic, Biogen Idec, Cambridge, Massachusetts
  1. Address correspondence to:
    Lin Xu, Drug Metabolism and Pharmacokinetic, Biogen Idec, Cambridge, MA 02142. E-mail: Lin.xu{at}biogenidec.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to December 2024

AbstractFullPdf
Aug 20174124
Sep 20177487
Oct 20174863
Nov 201711225
Dec 20179126
Jan 20187135
Feb 201811103
Mar 201811610
Apr 201812714
May 201862039
Jun 20182175
Jul 201821110
Aug 20184127
Sep 20181116
Oct 201861410
Nov 201862110
Dec 2018566
Jan 20191223
Feb 20191203
Mar 20192006
Apr 20191316
May 20192337
Jun 2019501
Jul 20192917
Aug 20194214
Oct 20192536
Nov 20192500
Dec 20192327
Jan 20201834
Feb 20202301
Mar 20201120
May 2020720
Jun 20203013
Jul 2020911
Aug 2020514
Sep 20201943
Oct 20201324
Nov 20201114
Dec 20202313
Jan 202121612
Feb 20212225
Mar 20212654
Apr 20211652
May 20211321
Jun 20211011
Jul 20212137
Aug 20211511
Sep 20211517
Oct 20211324
Nov 20212629
Dec 20217437
Jan 20222742
Feb 20222011
Mar 20221212
Apr 20221951
May 2022941
Jun 20223013
Jul 202229218
Aug 20221824
Sep 20221530
Oct 20221739
Nov 20221625
Dec 20221214
Jan 20232940
Feb 20231510
Mar 20232421
Apr 20239314
May 20234641
Jun 2023720
Jul 20232731
Aug 2023716
Sep 20231338
Oct 20232935
Nov 20231516
Dec 20233353
Jan 202447911
Feb 20242122
Mar 20242333
Apr 20241210
May 20242034
Jun 20243319
Jul 20244161
Aug 20243054
Sep 20242500
Oct 20241801
Nov 20241910
Dec 20243410

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

Metabolism of a Pyridinylmethyl-9H-purin-2-ylamine Analog

Lin Xu, Caroline Woodward, Jing Dai and Chandra Prakash
Drug Metabolism and Disposition December 1, 2013, 41 (12) 2133-2147; DOI: https://doi.org/10.1124/dmd.113.054023
Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement