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Research ArticleArticle

Metabolism and Excretion of Canagliflozin in Mice, Rats, Dogs, and Humans

Rao N. V. S. Mamidi, Filip Cuyckens, Jie Chen, Ellen Scheers, Dennis Kalamaridis, Ronghui Lin, Jose Silva, Sue Sha, David C. Evans, Michael F. Kelley, Damayanthi Devineni, Mark D. Johnson and Heng Keang Lim
Drug Metabolism and Disposition May 2014, 42 (5) 903-916; DOI: https://doi.org/10.1124/dmd.113.056440

Article Information

vol. 42 no. 5 903-916
DOI 
https://doi.org/10.1124/dmd.113.056440
PubMed 
24568888
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received December 11, 2013
  • Accepted February 25, 2014
  • Published online April 2, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Rao N. V. S. Mamidi,
  2. Filip Cuyckens,
  3. Jie Chen,
  4. Ellen Scheers,
  5. Dennis Kalamaridis,
  6. Ronghui Lin,
  7. Jose Silva,
  8. Sue Sha,
  9. David C. Evans,
  10. Michael F. Kelley,
  11. Damayanthi Devineni,
  12. Mark D. Johnson, and
  13. Heng Keang Lim
  1. Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
  1. Address correspondence to:
    Dr. Rao N. V. S. Mamidi, Janssen Research & Development, LLC, 1000 US Route 202, Raritan, NJ 08869. E-mail: smamidi1{at}its.jnj.com
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In Vivo Metabolism of Canagliflozin in Animals and Humans

Rao N. V. S. Mamidi, Filip Cuyckens, Jie Chen, Ellen Scheers, Dennis Kalamaridis, Ronghui Lin, Jose Silva, Sue Sha, David C. Evans, Michael F. Kelley, Damayanthi Devineni, Mark D. Johnson and Heng Keang Lim
Drug Metabolism and Disposition May 1, 2014, 42 (5) 903-916; DOI: https://doi.org/10.1124/dmd.113.056440
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