Research ArticleArticle
Metabolism and Excretion of Canagliflozin in Mice, Rats, Dogs, and Humans
Rao N. V. S. Mamidi, Filip Cuyckens, Jie Chen, Ellen Scheers, Dennis Kalamaridis, Ronghui Lin, Jose Silva, Sue Sha, David C. Evans, Michael F. Kelley, Damayanthi Devineni, Mark D. Johnson and Heng Keang Lim
Drug Metabolism and Disposition May 2014, 42 (5) 903-916; DOI: https://doi.org/10.1124/dmd.113.056440
Rao N. V. S. Mamidi
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Filip Cuyckens
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Jie Chen
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Ellen Scheers
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Dennis Kalamaridis
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Ronghui Lin
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Jose Silva
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Sue Sha
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
David C. Evans
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Michael F. Kelley
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Damayanthi Devineni
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Mark D. Johnson
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
Heng Keang Lim
Janssen Research & Development, Raritan, New Jersey (R.N.V.S.M., S.S., D.D., M.D.J.), Janssen Research & Development, Spring House, Pennsylvania (J.C., D.K., R.L., J.S., D.C.E., M.F.K., H.K.L.), and Janssen Research & Development, a division of Janssen Pharmaceutica NV, Beerse, Belgium (F.C., E.S.)
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In this issue
Research ArticleArticle
In Vivo Metabolism of Canagliflozin in Animals and Humans
Rao N. V. S. Mamidi, Filip Cuyckens, Jie Chen, Ellen Scheers, Dennis Kalamaridis, Ronghui Lin, Jose Silva, Sue Sha, David C. Evans, Michael F. Kelley, Damayanthi Devineni, Mark D. Johnson and Heng Keang Lim
Drug Metabolism and Disposition May 1, 2014, 42 (5) 903-916; DOI: https://doi.org/10.1124/dmd.113.056440
Research ArticleArticle
In Vivo Metabolism of Canagliflozin in Animals and Humans
Rao N. V. S. Mamidi, Filip Cuyckens, Jie Chen, Ellen Scheers, Dennis Kalamaridis, Ronghui Lin, Jose Silva, Sue Sha, David C. Evans, Michael F. Kelley, Damayanthi Devineni, Mark D. Johnson and Heng Keang Lim
Drug Metabolism and Disposition May 1, 2014, 42 (5) 903-916; DOI: https://doi.org/10.1124/dmd.113.056440
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