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Impact on Creatinine Renal Clearance by the Interplay of Multiple Renal Transporters: A Case Study with INCB039110

Yan Zhang, Mark S. Warren, Xuexiang Zhang, Sharon Diamond, Bill Williams, Naresh Punwani, Jane Huang, Yong Huang and Swamy Yeleswaram
Drug Metabolism and Disposition April 2015, 43 (4) 485-489; DOI: https://doi.org/10.1124/dmd.114.060673

Article Information

vol. 43 no. 4 485-489
DOI 
https://doi.org/10.1124/dmd.114.060673
PubMed 
25605813
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received August 16, 2014
  • Accepted January 20, 2015
  • Published online February 20, 2015.

Article Versions

Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yan Zhang,
  2. Mark S. Warren,
  3. Xuexiang Zhang,
  4. Sharon Diamond,
  5. Bill Williams,
  6. Naresh Punwani,
  7. Jane Huang,
  8. Yong Huang, and
  9. Swamy Yeleswaram
  1. Incyte Corporation, Wilmington, Delaware (Y.Z., S.D., B.W., N.P., S.Y.), and Optivia Biotechnology, Menlo Park, California (M.W., X.Z., J.H., Y.H.)
  1. Address correspondence to:
    Dr. Yan Zhang, Incyte Corporation, Route 141 & Henry Clay Rd, Wilmington, DE 19880. E-mail: yzhang{at}incyte.com
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Rapid CommunicationShort Communication

Creatinine Renal Clearance and the Interplay of Transporters

Yan Zhang, Mark S. Warren, Xuexiang Zhang, Sharon Diamond, Bill Williams, Naresh Punwani, Jane Huang, Yong Huang and Swamy Yeleswaram
Drug Metabolism and Disposition April 1, 2015, 43 (4) 485-489; DOI: https://doi.org/10.1124/dmd.114.060673
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