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Application of Mice Humanized for CYP2D6 to the Study of Tamoxifen Metabolism and Drug–Drug Interaction with Antidepressants

A. Kenneth MacLeod, Lesley A. McLaughlin, Colin J. Henderson and C. Roland Wolf
Drug Metabolism and Disposition January 2017, 45 (1) 17-22; DOI: https://doi.org/10.1124/dmd.116.073437

Article Information

vol. 45 no. 1 17-22
DOI 
https://doi.org/10.1124/dmd.116.073437
PubMed 
27756789
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 6, 2016
  • Accepted October 17, 2016
  • Published online December 8, 2016.

Article Versions

Copyright & Usage 
Copyright © 2016 The Author(s). This is an open access article distributed under the CC BY Attribution 4.0 International license.

Author Information

  1. A. Kenneth MacLeod,
  2. Lesley A. McLaughlin,
  3. Colin J. Henderson, and
  4. C. Roland Wolf
  1. Division of Cancer Research, Level 9, Jacqui Wood Cancer Centre, School of Medicine, University of Dundee, Dundee, DD1 9SY, United Kingdom
  1. Address correspondence to:
    C. Roland Wolf, Division of Cancer Research, Level 9, Jacqui Wood Cancer Centre, School of Medicine, University of Dundee, Ninewells Hospital, Dundee DD1 9SY, UK. E-mail: c.r.wolf{at}dundee.ac.uk
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Tamoxifen and Antidepressants in Humanized Mice

A. Kenneth MacLeod, Lesley A. McLaughlin, Colin J. Henderson and C. Roland Wolf
Drug Metabolism and Disposition January 1, 2017, 45 (1) 17-22; DOI: https://doi.org/10.1124/dmd.116.073437
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