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Research ArticleArticle

A Systematic In Vitro Investigation of the Inhibitor Preincubation Effect on Multiple Classes of Clinically Relevant Transporters

Péter Tátrai, Patrick Schweigler, Birk Poller, Norbert Domange, Roelof de Wilde, Imad Hanna, Zsuzsanna Gáborik and Felix Huth
Drug Metabolism and Disposition July 2019, 47 (7) 768-778; DOI: https://doi.org/10.1124/dmd.118.085993

Article Information

vol. 47 no. 7 768-778
DOI 
https://doi.org/10.1124/dmd.118.085993
PubMed 
31068368
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 8, 2019
  • Accepted May 2, 2019
  • Published online June 18, 2019.

Article Versions

Copyright & Usage 
Copyright © 2019 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Péter Tátrai⇑,
  2. Patrick Schweigler,
  3. Birk Poller,
  4. Norbert Domange,
  5. Roelof de Wilde,
  6. Imad Hanna,
  7. Zsuzsanna Gáborik, and
  8. Felix Huth⇑
  1. Solvo Biotechnology, Budapest, Hungary (P.T., R.d.W., Z.G.); Novartis Institutes for Biomedical Research, Basel, Switzerland (P.S., B.P., N.D., F.H.); and Novartis Institutes for Biomedical Research, East Hanover, New Jersey (I.H.)
  1. Address correspondence to:
    Dr. Felix Huth, PK Science – In vitro ADME, Novartis Pharma AG, Novartis Institutes of BioMedical Research, Novartis Campus St. Johann, Fabrikstr. 14, CH-4002 Basel, Switzerland. E-mail: felix.huth{at}novartis.com; or
  2. Dr. Péter Tátrai, Research & Development, Solvo Biotechnology, Science Park, Building B2, 4-20 Irinyi J. Str., H-1117 Budapest, Hungary. E-mail: tatrai{at}solvo.com
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Research ArticleArticle

A Systematic Investigation of Inhibitor Preincubation

Péter Tátrai, Patrick Schweigler, Birk Poller, Norbert Domange, Roelof de Wilde, Imad Hanna, Zsuzsanna Gáborik and Felix Huth
Drug Metabolism and Disposition July 1, 2019, 47 (7) 768-778; DOI: https://doi.org/10.1124/dmd.118.085993
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