Research ArticleArticle
In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver
Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
Drug Metabolism and Disposition April 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126
Yurie Katsube
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Masayuki Tsujimoto
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Hiroyoshi Koide
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Daiki Hira
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Yoshito Ikeda
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Tetsuya Minegaki
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Shin-ya Morita
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Tomohiro Terada
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
Kohshi Nishiguchi
Department of Clinical Pharmacy, Kyoto Pharmaceutical University, Kyoto, Japan (Y.K., M.T., H.K., T.M., K.N.); Department of Pharmacy, Shiga University of Medical Science Hospital, Shiga, Japan (D.H., Y.I., S.-y.M., T.T.); and College of Pharmaceutical Sciences, Ritsumeikan University, Shiga, Japan (D.H.)
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Research ArticleArticle
Candesartan Glucuronide Serves as a CYP2C8 Inhibitor
Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
Drug Metabolism and Disposition April 1, 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126
Research ArticleArticle
Candesartan Glucuronide Serves as a CYP2C8 Inhibitor
Yurie Katsube, Masayuki Tsujimoto, Hiroyoshi Koide, Daiki Hira, Yoshito Ikeda, Tetsuya Minegaki, Shin-ya Morita, Tomohiro Terada and Kohshi Nishiguchi
Drug Metabolism and Disposition April 1, 2021, 49 (4) 289-297; DOI: https://doi.org/10.1124/dmd.120.000126
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