Data Supplement

Files in this Data Supplement:

• Supplemental Data -

  Supplemental Table 1 - Electrospray Ionization Tandem Mass Spectrometry (ESI-MS/MS) based on mass to charge ratio (m/z) with a proton adducts M+H+ parameters...

  Supplemental Table 2 - LC-MS/MS system performance test...

  Supplemental Table 3 - Between day precision and accuracy of calibration curve standards (CC, n=6) and four level quality control (QC, n=18) standards...

  Supplemental Table 4 - Recovery and matrix effect of two levels of quality control (QC, n=6) standards...

  Supplemental Table 5 - Bench top (250C ) and Freeze thaw (-800C) for stability four cycle quality control (QC, n=6) standards...

  Supplemental Table 6 - The statistical results of d-MA docked into the active sites of four CYP enzymes...

  Supplemental Table 7 - The statistical results of l-MA docked into the active sites of four CYP enzymes

  Supplemental Figure 1 - l-MA binds at the active site of human CYP2D6...