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THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL

Angela Doran, R. Scott Obach, Bill J. Smith, Natilie A. Hosea, Stacey Becker, Ernesto Callegari, Cuiping Chen, Xi Chen, Edna Choo, Julie Cianfrogna, Loretta M. Cox, John P. Gibbs, Megan A. Gibbs, Heather Hatch, Cornelis E.C.A. Hop, Ilana N. Kasman, Jennifer LaPerle, JianHua Liu, Xingrong Liu, Michael Logman, Debra Maclin, Frank M. Nedza, Frederick Nelson, Emily Olson, Sandhya Rahematpura, David Raunig, Sabrinia Rogers, Kari Schmidt, Douglas K. Spracklin, Mark Szewc, Matthew Troutman, Elaine Tseng, Meihua Tu, Jeffrey W. Van Deusen, Karthik Venkatakrishnan, Gary Walens, Ellen Q. Wang, Diane Wong, Adam S. Yasgar and Chenghong Zhang
Drug Metabolism and Disposition January 2005, 33 (1) 165-174; DOI: https://doi.org/10.1124/dmd.104.001230

 

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Research ArticleArticle

THE IMPACT OF P-GLYCOPROTEIN ON THE DISPOSITION OF DRUGS TARGETED FOR INDICATIONS OF THE CENTRAL NERVOUS SYSTEM: EVALUATION USING THE MDR1A/1B KNOCKOUT MOUSE MODEL

Angela Doran, R. Scott Obach, Bill J. Smith, Natilie A. Hosea, Stacey Becker, Ernesto Callegari, Cuiping Chen, Xi Chen, Edna Choo, Julie Cianfrogna, Loretta M. Cox, John P. Gibbs, Megan A. Gibbs, Heather Hatch, Cornelis E.C.A. Hop, Ilana N. Kasman, Jennifer LaPerle, JianHua Liu, Xingrong Liu, Michael Logman, Debra Maclin, Frank M. Nedza, Frederick Nelson, Emily Olson, Sandhya Rahematpura, David Raunig, Sabrinia Rogers, Kari Schmidt, Douglas K. Spracklin, Mark Szewc, Matthew Troutman, Elaine Tseng, Meihua Tu, Jeffrey W. Van Deusen, Karthik Venkatakrishnan, Gary Walens, Ellen Q. Wang, Diane Wong, Adam S. Yasgar and Chenghong Zhang
Drug Metabolism and Disposition January 1, 2005, 33 (1) 165-174; DOI: https://doi.org/10.1124/dmd.104.001230
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