Research ArticleArticle
Open Access
Comparison of 19F NMR and 14C Measurements for the Assessment of ADME of BYL719 (Alpelisib) in Humans
Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
Drug Metabolism and Disposition August 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424
Alexander David James
PK Sciences (ADME), Novartis Institutes for Biomedical Research, Basel, Switzerland (A.D.J., C.M., G.C.); and AX, Global Discovery Chemistry, Novartis Institutes for Biomedical Research Basel, Switzerland (A.L., A.M.)
Cyrille Marvalin
PK Sciences (ADME), Novartis Institutes for Biomedical Research, Basel, Switzerland (A.D.J., C.M., G.C.); and AX, Global Discovery Chemistry, Novartis Institutes for Biomedical Research Basel, Switzerland (A.L., A.M.)
Alexandre Luneau
PK Sciences (ADME), Novartis Institutes for Biomedical Research, Basel, Switzerland (A.D.J., C.M., G.C.); and AX, Global Discovery Chemistry, Novartis Institutes for Biomedical Research Basel, Switzerland (A.L., A.M.)
Axel Meissner
PK Sciences (ADME), Novartis Institutes for Biomedical Research, Basel, Switzerland (A.D.J., C.M., G.C.); and AX, Global Discovery Chemistry, Novartis Institutes for Biomedical Research Basel, Switzerland (A.L., A.M.)
Gian Camenisch
PK Sciences (ADME), Novartis Institutes for Biomedical Research, Basel, Switzerland (A.D.J., C.M., G.C.); and AX, Global Discovery Chemistry, Novartis Institutes for Biomedical Research Basel, Switzerland (A.L., A.M.)
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Research ArticleArticle
Use of 19F NMR To Assess ADME of Alpelisib
Alexander David James, Cyrille Marvalin, Alexandre Luneau, Axel Meissner and Gian Camenisch
Drug Metabolism and Disposition August 1, 2017, 45 (8) 900-907; DOI: https://doi.org/10.1124/dmd.117.075424
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