Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice

Junichi Takano; Kazuya Maeda; Hiroyuki Kusuhara; Yuichi Sugiyama

doi:10.1124/dmd.117.079483

Research ArticleSpecial Section on Transporters in Drug Disposition and Pharmacokinetic Prediction

Organic Anion Transporting Polypeptide 1a4 is Responsible for the Hepatic Uptake of Cardiac Glycosides in Mice

Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama

Drug Metabolism and Disposition May 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483

Junichi Takano

Kyorin Pharmaceutical Co., LTD, Tokyo, Japan (J.T.); Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.M., H.K.); and Sugiyama Laboratory, RIKEN Innovation Center, RIKEN Cluster for Industry Partnerships, RIKEN, Yokohama, Japan (Y.S.)

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Kazuya Maeda

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Hiroyuki Kusuhara

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Yuichi Sugiyama

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Drug Metabolism and Disposition

Vol. 46, Issue 5

1 May 2018

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Research ArticleSpecial Section on Transporters in Drug Disposition and Pharmacokinetic Prediction

Oatp1a4-Mediated Hepatic Uptake of Cardiac Glycosides

Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama

Drug Metabolism and Disposition May 1, 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483

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Research ArticleSpecial Section on Transporters in Drug Disposition and Pharmacokinetic Prediction

Oatp1a4-Mediated Hepatic Uptake of Cardiac Glycosides

Junichi Takano, Kazuya Maeda, Hiroyuki Kusuhara and Yuichi Sugiyama

Drug Metabolism and Disposition May 1, 2018, 46 (5) 652-657; DOI: https://doi.org/10.1124/dmd.117.079483

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