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Research ArticleSpecial Section on Transporters in Drug Disposition and Pharmacokinetic Prediction

Prediction of the Effects of Renal Impairment on Clearance for Organic Cation Drugs that Undergo Renal Secretion: A Simulation-Based Study

Kristin E. Follman and Marilyn E. Morris
Drug Metabolism and Disposition May 2018, 46 (5) 758-769; DOI: https://doi.org/10.1124/dmd.117.079558

Article Information

vol. 46 no. 5 758-769
DOI 
https://doi.org/10.1124/dmd.117.079558
PubMed 
29490902
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 19, 2017
  • Accepted February 21, 2018
  • Published online April 10, 2018.

Article Versions

Copyright & Usage 
Copyright © 2018 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kristin E. Follman and
  2. Marilyn E. Morris
  1. Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, New York
  1. Address correspondence to:
    Dr. Marilyn E. Morris, Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, University at Buffalo, State University of New York, Buffalo, NY 14214. E-mail: memorris{at}buffalo.edu
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Research ArticleSpecial Section on Transporters in Drug Disposition and Pharmacokinetic Prediction

Effects of RI on Renal Secretion of OCT Substrates

Kristin E. Follman and Marilyn E. Morris
Drug Metabolism and Disposition May 1, 2018, 46 (5) 758-769; DOI: https://doi.org/10.1124/dmd.117.079558
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