Research ArticleArticle
Open Access
Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice
Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
Drug Metabolism and Disposition August 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718
Y. Kapelyukh
Systems Medicine, School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, United Kingdom (Y.K., C.J.H., C.R.W.) and Taconic Biosciences Inc., Rensselaer, New York (N.S., A.R.)
C. J. Henderson
Systems Medicine, School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, United Kingdom (Y.K., C.J.H., C.R.W.) and Taconic Biosciences Inc., Rensselaer, New York (N.S., A.R.)
N. Scheer
Systems Medicine, School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, United Kingdom (Y.K., C.J.H., C.R.W.) and Taconic Biosciences Inc., Rensselaer, New York (N.S., A.R.)
A. Rode
Systems Medicine, School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, United Kingdom (Y.K., C.J.H., C.R.W.) and Taconic Biosciences Inc., Rensselaer, New York (N.S., A.R.)
C. R. Wolf
Systems Medicine, School of Medicine, University of Dundee, Jacqui Wood Cancer Centre, Ninewells Hospital, Dundee, United Kingdom (Y.K., C.J.H., C.R.W.) and Taconic Biosciences Inc., Rensselaer, New York (N.S., A.R.)
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hCYP1A1/1A2 Mice for Drug Interaction Studies
Y. Kapelyukh, C. J. Henderson, N. Scheer, A. Rode and C. R. Wolf
Drug Metabolism and Disposition August 1, 2019, 47 (8) 907-918; DOI: https://doi.org/10.1124/dmd.119.087718
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